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What exactly is metronidazole, and how is it utilized?

Metronidazole serves as an antibiotic that effectively combats anaerobic bacteria and specific parasites. Anaerobic bacteria, which are single-celled microorganisms, flourish in oxygen-deprived conditions. These bacteria can instigate illnesses in diverse areas of the body such as the abdomen (bacterial peritonitis), liver (liver abscess), and pelvis (abscesses in the ovaries and Fallopian tubes). Furthermore, intestinal parasites like Giardia lamblia and ameba may induce abdominal discomfort and diarrhea. The vaginal parasite Trichomonas induces vaginal inflammation (vaginitis). Metronidazole specifically impedes several functions within bacterial cells and parasites, ultimately causing their demise.


Metronidazole proves effective in dealing with a variety of ailments, such as eradicating parasitic invaders like Giardia that plague the bowels, resolving liver abscesses caused by amoebas, and alleviating the discomfort of amoebic dysentery that results in bloody stool. In addition, it can combat bacterial vaginosis, address trichomonas infections in the vaginal area, and eliminate carriers of trichomonas (including sexual partners) even if they show no signs of illness. Furthermore, when combined with other antibiotics, Metronidazole aids in the treatment of abscesses forming in the liver, pelvis, abdomen, and brain due to anaerobic bacteria that are susceptible to its effects.

Metronidazole plays a crucial role in combatting bacterial infections, such as those caused by the sneaky bacterium C. difficile in the colon. Various antibiotics can stir up trouble by changing the bacterial landscape in the gut, paving the way for C. difficile to wreak havoc and lead to nasty symptoms like colonic inflammation and agonizing diarrhea. Additionally, Metronidazole teams up with other medications to take down the notorious Helicobacter pylori, the culprit behind stomach and intestinal ulcers.

Topical gel containing metronidazole is commonly prescribed to address the symptoms of acne rosacea. Metronidazole gel for vaginal use is typically recommended for the treatment of bacterial vaginosis.

What is the recommended metronidazole dosage?

Metronidazole can be ingested orally, either on an empty stomach or with food. In medical settings, metronidazole can also be administered intravenously to combat severe infections. The liver plays a crucial role in metabolizing metronidazole, and dosage adjustments might be necessary in individuals with liver impairment. Different metronidazole treatment schedules are available, with a few examples outlined below.

Treatment for different conditions using specific dosages at different intervals for a certain number of days include eliminating parasitic infections, managing bacterial imbalances, and combating anaerobic infections. Dosage regimens range from daily oral consumption to intravenous injections, varied by the type of infection and severity levels.

Giardia: A regimen of 250 mg metronidazole taken orally three times a day for 5 days, Helicobacter pylori: The recommended dosage of metronidazole is 800-1500 mg orally per day for multiple days alongside other medications. Pelvic inflammatory disease (PID): A course of 500 mg metronidazole taken orally twice daily for 14 days in combination with other drugs. Trichomoniasis: A single 2 g dose or 1 g taken twice. Rosacea: Application of topical gel containing 0.75-1% metronidazole once daily.

What is the appropriate metronidazole dose?

Metronidazole can be ingested orally, regardless of food intake. In hospital settings, metronidazole can be administered intravenously to address severe infections.

The liver plays a major role in getting rid of metronidazole from the system, so it might be necessary to lower the doses for individuals with liver problems. There are different metronidazole treatment plans available, such as the following examples.

  • For amoebic dysentery: Take 750 mg orally three times a day for 5-10 days.
  • For amoebic liver abscess: Take 500-750 mg orally three times a day for 5-10 days.
  • For anaerobic infections: Administer 7.5 mg/kg orally or through injections every 6 hours for 7 to 10 days, with a maximum daily limit of 4 grams.
  • For bacterial vaginosis: Take 750 mg (extended release tablets) once daily for 7 days, or 500 mg twice daily for 7 days, or a 2 g single dose, or apply one full applicator of 0.75% vaginal gel once or twice daily for 5 days.
  • Ingesting Metronidazole, in specified doses and frequencies, is recommended for combating multiple types of infections caused by parasites and bacteria in different parts of the body, such as the genital region, skin, abdominal area, blood, bones, joints, nervous system, and the cardiac muscle.

    For example, hissy fit, vagabondage bacteria, by the way suffering in the pelvic area (PIA), C. difficile, H. pylori, STDs (trichomonas), rosacea acne, peritonitis, endometriosis, endomyometritis, tubulo-ovarian abscess, bacterial septicemia, meningitis, purulent brain abscess, pneumonia, interpretation of pulmonary abscess and endocarditis.


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